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MHRA

MHRA Drug Safety Alert: Dorzolomide hydrochloride/timolol maleate (Cosopt) preservative-free single-dose eye drops: reports of eye injury

Dorzolomide hydrochloride/timolol maleate (Cosopt) preservative-free single-dose eye drops are used to treat glaucoma. The MHRA is aware of 69 complaints in the UK with this product after the introduction of a new design of dropper in July 2013. These reports include scratches to the cornea, and difficulty in administration of the drops onto the eye.

MHRA Drug Safety Update Risperidone & paliperidone:risk of intraoperative floppy iris syndrome in patients undergoing cataract surgery

The Medicines and Healthcare Products Regulatory Agency has issued a Drug Safety Update to alert medical professionals to cases of intraoperative floppy iris syndrome (IFIS) during cataract surgery  reported in patients taking the atypical antipsychotics risperidone or paliperidone. IFIS may increase the risk of eye complications during and after cataract surgery Risperidone & paliperidone:risk of