Service guidance
  • Cataract
  • Cornea
  • Glaucoma

Managing an outbreak of postoperative endophthalmitis

  • Last updated or reviewed: 1 January 2022
  • First published: 1 January 2022
Managing-an-endophthalmitis-outbreak (PDF)

Guidance for ophthalmology teams on identifying, managing and investigating outbreaks of postoperative endophthalmitis. Supports rapid response, patient safety, and service continuity across cataract and other intraocular procedures.

This guidance supports ophthalmology teams in recognising, managing and investigating suspected outbreaks of postoperative endophthalmitis. It focuses on cataract surgery but applies across intraocular procedures, including intravitreal injections and glaucoma surgery. 

It outlines early warning signs, thresholds for concern, and immediate actions required to reduce patient harm. The document provides practical advice on notification, multidisciplinary working, and when to pause surgical activity. It also details investigation processes, including microbiological sampling, environmental review, and audit of theatre practices. 

Clear emphasis is placed on prevention through robust theatre protocols, surveillance of complication rates, and continuous clinical governance. A structured flowchart and checklist support rapid, consistent decision-making during suspected outbreaks.